Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor types, being lowest in sarcomas, whereas 90% of pancreatic ductal adenocarcinoma (PDAC) patients experience severe weight loss. How these tumors...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dev Cell
Auteurs principaux: Parajuli, Parash, Kumar, Santosh, Loumaye, Audrey, Singh, Purba, Eragamreddy, Sailaja, Nguyen, Thien Ly, Ozkan, Seval, Razzaque, Mohammed S., Prunier, Céline, Thissen, Jean-Paul, Atfi, Azeddine
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054474/
https://ncbi.nlm.nih.gov/pubmed/29920276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.026
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