Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia

Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor types, being lowest in sarcomas, whereas 90% of pancreatic ductal adenocarcinoma (PDAC) patients experience severe weight loss. How these tumors...

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Veröffentlicht in:Dev Cell
Hauptverfasser: Parajuli, Parash, Kumar, Santosh, Loumaye, Audrey, Singh, Purba, Eragamreddy, Sailaja, Nguyen, Thien Ly, Ozkan, Seval, Razzaque, Mohammed S., Prunier, Céline, Thissen, Jean-Paul, Atfi, Azeddine
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054474/
https://ncbi.nlm.nih.gov/pubmed/29920276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.05.026
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