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TGIF1-Twist1 axis in pancreatic ductal adenocarcinoma
TG-interacting factor 1 (TGIF1) exerts inhibitory effects on transforming growth factor-beta (TGF-β) signaling by suppressing Smad signaling pathway at multiple levels. TGIF1 activity is important for normal embryogenesis and organogenesis, yet its dysregulation can culminate in tumorigenesis. For i...
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| Veröffentlicht in: | Comput Struct Biotechnol J |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Research Network of Computational and Structural Biotechnology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520386/ https://ncbi.nlm.nih.gov/pubmed/33005315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.09.023 |
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