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Leptin-induced Trafficking of K(ATP) Channels: A Mechanism to Regulate Pancreatic β-cell Excitability and Insulin Secretion

The adipocyte hormone leptin was first recognized for its actions in the central nervous system to regulate energy homeostasis but has since been shown to have direct actions on peripheral tissues. In pancreatic β-cells leptin suppresses insulin secretion by increasing K(ATP) channel conductance, wh...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cochrane, Veronica, Shyng, Show-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600549/
https://ncbi.nlm.nih.gov/pubmed/31151172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112660
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