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NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells

NMDA receptors (NMDARs) are Ca(2+)-permeant, ligand-gated ion channels activated by the excitatory neurotransmitter glutamate and have well-characterized roles in the nervous system. The expression and function of NMDARs in pancreatic β-cells, by contrast, are poorly understood. Here, we report a no...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Yi, Fortin, Dale A., Cochrane, Veronica A., Chen, Pei-Chun, Shyng, Show-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602408/
https://ncbi.nlm.nih.gov/pubmed/28768770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802249
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