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Concerted Trafficking Regulation of Kv2.1 and K(ATP) Channels by Leptin in Pancreatic β-Cells
In pancreatic β-cells, voltage-gated potassium 2.1 (Kv2.1) channels are the dominant delayed rectifier potassium channels responsible for action potential repolarization. Here, we report that leptin, a hormone secreted by adipocytes known to inhibit insulin secretion, causes a transient increase in...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705974/ https://ncbi.nlm.nih.gov/pubmed/26453299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.670877 |
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