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AKAP79/150 coordinates leptin-induced PKA signaling to regulate K(ATP) channel trafficking in pancreatic β-cells

The adipocyte hormone leptin regulates glucose homeostasis both centrally and peripherally. A key peripheral target is the pancreatic β-cell, which secretes insulin upon glucose stimulation. Leptin is known to suppress glucose-stimulated insulin secretion by promoting trafficking of K(ATP) channels...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Cochrane, Veronica A., Yang, Zhongying, Dell'Acqua, Mark L., Shyng, Show-Ling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010710/
https://ncbi.nlm.nih.gov/pubmed/33617875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100442
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