Leptin Suppression of Insulin Secretion by the Activation of ATP-Sensitive K(+) Channels in Pancreatic β-Cells

In the genetic mutant mouse models ob/ob or db/db, leptin deficiency or resistance, respectively, results in severe obesity and the development of a syndrome resembling NIDDM. One of the earliest manifestations in these mutant mice is hyperinsulinemia, suggesting that leptin may normally directly su...

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Bibliografiske detaljer
Main Authors:	Kieffer, Timothy J., Heller, R. Scott, Leech, Colin A., Holz, George G., Habener, Joel F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	1997
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2940064/ https://ncbi.nlm.nih.gov/pubmed/9166685
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Leptin Suppression of Insulin Secretion by the Activation of ATP-Sensitive K(+) Channels in Pancreatic β-Cells

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