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Evolving neoantigen profiles in colorectal cancers with DNA repair defects
BACKGROUND: Neoantigens that arise as a consequence of tumor-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In colorectal cancer (CRC) and other tumor types, a high number of neoantigens is associated with patient response to immune therapies. The mol...
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| Publicado no: | Genome Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599263/ https://ncbi.nlm.nih.gov/pubmed/31253177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0654-6 |
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