Evolving neoantigen profiles in colorectal cancers with DNA repair defects

BACKGROUND: Neoantigens that arise as a consequence of tumor-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In colorectal cancer (CRC) and other tumor types, a high number of neoantigens is associated with patient response to immune therapies. The mol...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Rospo, Giuseppe, Lorenzato, Annalisa, Amirouchene-Angelozzi, Nabil, Magrì, Alessandro, Cancelliere, Carlotta, Corti, Giorgio, Negrino, Carola, Amodio, Vito, Montone, Monica, Bartolini, Alice, Barault, Ludovic, Novara, Luca, Isella, Claudio, Medico, Enzo, Bertotti, Andrea, Trusolino, Livio, Germano, Giovanni, Di Nicolantonio, Federica, Bardelli, Alberto
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599263/
https://ncbi.nlm.nih.gov/pubmed/31253177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0654-6
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