Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer

The long-term efficacy of the Epidermal Growth Factor Receptor (EGFR)-targeted antibody cetuximab in advanced colorectal cancer (CRC) patients is limited by the emergence of drug-resistant (persister) cells. Recent studies in other cancer types have shown that cells surviving initial treatment with...

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Udgivet i:Cancers (Basel)
Main Authors: Lorenzato, Annalisa, Magrì, Alessandro, Matafora, Vittoria, Audrito, Valentina, Arcella, Pamela, Lazzari, Luca, Montone, Monica, Lamba, Simona, Deaglio, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Bachi, Angela, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140052/
https://ncbi.nlm.nih.gov/pubmed/32183295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030685
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