7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

[Image: see text] Mitragyna speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction. Recently, growing use of the plant in the United States and concerns that kratom r...

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Publicado en:ACS Cent Sci
Main Authors: Kruegel, Andrew C., Uprety, Rajendra, Grinnell, Steven G., Langreck, Cory, Pekarskaya, Elizabeth A., Le Rouzic, Valerie, Ansonoff, Michael, Gassaway, Madalee M., Pintar, John E., Pasternak, Gavril W., Javitch, Jonathan A., Majumdar, Susruta, Sames, Dalibor
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2019
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598159/
https://ncbi.nlm.nih.gov/pubmed/31263758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00141
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