Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis

The Myc gene is a universal oncogene that promotes aggressive cancer, but its role in metastasis has remained elusive. Here, we show that Myc transcriptionally controls a gene network of subcellular mitochondrial trafficking that includes the atypical mitochondrial GTPases RHOT1 and RHOT2, the adapt...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Agarwal, Ekta, Altman, Brian J., Ho Seo, Jae, Bertolini, Irene, Ghosh, Jagadish C., Kaur, Amanpreet, Kossenkov, Andrew V., Languino, Lucia R., Gabrilovich, Dmitry I., Speicher, David W., Dang, Chi V., Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597883/
https://ncbi.nlm.nih.gov/pubmed/31061095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00109-19
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