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Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis

The Myc gene is a universal oncogene that promotes aggressive cancer, but its role in metastasis has remained elusive. Here, we show that Myc transcriptionally controls a gene network of subcellular mitochondrial trafficking that includes the atypical mitochondrial GTPases RHOT1 and RHOT2, the adapt...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Agarwal, Ekta, Altman, Brian J., Ho Seo, Jae, Bertolini, Irene, Ghosh, Jagadish C., Kaur, Amanpreet, Kossenkov, Andrew V., Languino, Lucia R., Gabrilovich, Dmitry I., Speicher, David W., Dang, Chi V., Altieri, Dario C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597883/
https://ncbi.nlm.nih.gov/pubmed/31061095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00109-19
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