SYNTAPHILIN UBIQUITINATION REGULATES MITOCHONDRIAL DYNAMICS AND TUMOR CELL MOVEMENTS

Syntaphilin (SNPH) inhibits the movement of mitochondria in tumor cells, preventing their accumulation at the cortical cytoskeleton and limiting the bioenergetics of cell motility and invasion. Although this may suppress metastasis, the regulation of the SNPH pathway is not well understood. Using a...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Seo, Jae Ho, Agarwal, Ekta, Bryant, Kelly G., Caino, M. Cecilia, Kim, Eui Tae, Kossenkov, Andrew V., Tang, Hsin-Yao, Languino, Lucia R., Gabrilovich, Dmitry I., Cohen, Andrew R., Speicher, David W., Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072605/
https://ncbi.nlm.nih.gov/pubmed/29898993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0595
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