The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation–suppressing activity

Heat shock protein family B (small) member 7 (HSPB7) is a unique, relatively unexplored member within the family of human small heat shock proteins (HSPBs). Unlike most HSPB family members, HSPB7 does not oligomerize and so far has not been shown to associate with any other member of the HSPB family...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Wu, Di, Vonk, Jan J., Salles, Felix, Vonk, Danara, Haslbeck, Martin, Melki, Ronald, Bergink, Steven, Kampinga, Harm H.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597824/
https://ncbi.nlm.nih.gov/pubmed/31097540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007117
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