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Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING
Interleukin-1 beta (IL-1β) is a pleiotropic mediator of inflammation and is produced in response to a wide range of stimuli. During infection, IL-1β production occurs in parallel with the onset of innate antimicrobial defenses, but the contribution of IL-1β signaling to cell-intrinsic immunity is no...
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| Publicat a: | Mol Cell |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596306/ https://ncbi.nlm.nih.gov/pubmed/30952515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.038 |
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