Dimethyl fumarate reprograms cervical cancer cells to enhance antitumor immunity by activating mtDNA-cGAS-STING pathway

Abstract Background Cervical cancer (CC) remains a significant global health challenge for women, especially in advanced stages where effective treatments are limited. Current immunotherapies, including PD-1/PD-L1 blockades and adoptive T cell therapies, show limited response rates and durability. D...

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主要な著者:	Han Jiang, Liting Liu, Shan He, Shen Qu, Yifan Yang, Guijie Kang, Min Wu, Hangyu Liu, Yuwei Zhang, Zixuan Wang, Wenjing Tian, Ying Chen, Liming Wang, Qiangqiang Wang, Ting Ye, Junyan Han, Hui Wang, Yafei Huang
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-10-01
シリーズ:	Journal of Biomedical Science
主題:	Immunotherapy CD8+ T CXCL10 CCL5 Dimethyl fumarate Cervical cancer
オンライン･アクセス:	https://doi.org/10.1186/s12929-025-01187-x
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