QR Code

Dimethyl fumarate reprograms cervical cancer cells to enhance antitumor immunity by activating mtDNA-cGAS-STING pathway

Abstract Background Cervical cancer (CC) remains a significant global health challenge for women, especially in advanced stages where effective treatments are limited. Current immunotherapies, including PD-1/PD-L1 blockades and adoptive T cell therapies, show limited response rates and durability. D...

Full description

Saved in:
Main Authors: Han Jiang, Liting Liu, Shan He, Shen Qu, Yifan Yang, Guijie Kang, Min Wu, Hangyu Liu, Yuwei Zhang, Zixuan Wang, Wenjing Tian, Ying Chen, Liming Wang, Qiangqiang Wang, Ting Ye, Junyan Han, Hui Wang, Yafei Huang
Format: Artigo
Language:Inglês
Published: BMC 2025-10-01
Series:Journal of Biomedical Science
Subjects:
Immunotherapy
CD8+ T
CXCL10
CCL5
Dimethyl fumarate
Cervical cancer
Online Access:https://doi.org/10.1186/s12929-025-01187-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items