Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias

The lack of predictive preclinical models is a fundamental barrier to translating knowledge about the molecular pathogenesis of cancer into improved therapies. Insertional mutagenesis (IM) in mice is a robust strategy for generating malignancies that recapitulate the extensive inter- and intra-tumor...

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Udgivet i:PLoS Genet
Main Authors: Huang, Benjamin J., Wandler, Anica M., Meyer, Lauren K., Dail, Monique, Daemen, Anneleen, Sampath, Deepak, Li, Qing, Wang, Xinyue, Wong, Jasmine C., Nakitandwe, Joy, Downing, James R., Zhang, Jinghui, Taylor, Barry S., Shannon, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594654/
https://ncbi.nlm.nih.gov/pubmed/31199785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008168
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