Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias

The lack of predictive preclinical models is a fundamental barrier to translating knowledge about the molecular pathogenesis of cancer into improved therapies. Insertional mutagenesis (IM) in mice is a robust strategy for generating malignancies that recapitulate the extensive inter- and intra-tumor...

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Publicat a:PLoS Genet
Autors principals: Huang, Benjamin J., Wandler, Anica M., Meyer, Lauren K., Dail, Monique, Daemen, Anneleen, Sampath, Deepak, Li, Qing, Wang, Xinyue, Wong, Jasmine C., Nakitandwe, Joy, Downing, James R., Zhang, Jinghui, Taylor, Barry S., Shannon, Kevin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594654/
https://ncbi.nlm.nih.gov/pubmed/31199785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008168
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