Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias

The lack of predictive preclinical models is a fundamental barrier to translating knowledge about the molecular pathogenesis of cancer into improved therapies. Insertional mutagenesis (IM) in mice is a robust strategy for generating malignancies that recapitulate the extensive inter- and intra-tumor...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Huang, Benjamin J., Wandler, Anica M., Meyer, Lauren K., Dail, Monique, Daemen, Anneleen, Sampath, Deepak, Li, Qing, Wang, Xinyue, Wong, Jasmine C., Nakitandwe, Joy, Downing, James R., Zhang, Jinghui, Taylor, Barry S., Shannon, Kevin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594654/
https://ncbi.nlm.nih.gov/pubmed/31199785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008168
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