ERdj5 in Innate Immune Cells Is a Crucial Factor for the Mucosal Adjuvanticity of Cholera Toxin

Cholera toxin (CT) is one of most strong mucosal adjuvants, but it cannot be clinically used owing to its toxicity. The cytosolic A1 subunit of CT (CTA1) is the molecule responsible for its immunostimulatory activity, which increases the concentration of cyclic AMP and causes the induction of pro-in...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Kim, Mee-Sun, Yi, Eun-Je, Kim, Young-In, Kim, So Hee, Jung, Yi-Sook, Kim, Seong-Ryeol, Iwawaki, Takao, Ko, Hyun-Jeong, Chang, Sun-Young
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593289/
https://ncbi.nlm.nih.gov/pubmed/31275300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01249
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