ERdj5 in Innate Immune Cells Is a Crucial Factor for the Mucosal Adjuvanticity of Cholera Toxin

Cholera toxin (CT) is one of most strong mucosal adjuvants, but it cannot be clinically used owing to its toxicity. The cytosolic A1 subunit of CT (CTA1) is the molecule responsible for its immunostimulatory activity, which increases the concentration of cyclic AMP and causes the induction of pro-in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kim, Mee-Sun, Yi, Eun-Je, Kim, Young-In, Kim, So Hee, Jung, Yi-Sook, Kim, Seong-Ryeol, Iwawaki, Takao, Ko, Hyun-Jeong, Chang, Sun-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593289/
https://ncbi.nlm.nih.gov/pubmed/31275300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01249
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