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The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation
Cholera toxin (CT) traffics from the host cell surface to the endoplasmic reticulum (ER), where the toxin's catalytic CTA1 subunit retrotranslocates to the cytosol to induce toxicity. In the ER, CT is captured by the E3 ubiquitin ligase Hrd1 via an undefined mechanism to prepare for retrotransl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596249/ https://ncbi.nlm.nih.gov/pubmed/23363602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0522 |
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