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Photoredox-Catalyzed Enantioselective α-Deuteration of Azaarenes with D(2)O

The site-specific incorporation of deuterium (D) into small molecules is frequently used to access isotopically labeled compounds with broad utility in many research areas, such as drug development, mechanistic studies, and NMR analyses. Nevertheless, the deuteration of a stereocenter in an enantios...

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Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Shao, Tianju, Li, Yajuan, Ma, Nana, Li, Chunyang, Chai, Guobi, Zhao, Xiaowei, Qiao, Baokun, Jiang, Zhiyong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593145/
https://ncbi.nlm.nih.gov/pubmed/31229890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.007
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