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Photoredox-Catalyzed Enantioselective α-Deuteration of Azaarenes with D(2)O

The site-specific incorporation of deuterium (D) into small molecules is frequently used to access isotopically labeled compounds with broad utility in many research areas, such as drug development, mechanistic studies, and NMR analyses. Nevertheless, the deuteration of a stereocenter in an enantios...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Shao, Tianju, Li, Yajuan, Ma, Nana, Li, Chunyang, Chai, Guobi, Zhao, Xiaowei, Qiao, Baokun, Jiang, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593145/
https://ncbi.nlm.nih.gov/pubmed/31229890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.007
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