Photoredox-Catalyzed Enantioselective α-Deuteration of Azaarenes with D(2)O

The site-specific incorporation of deuterium (D) into small molecules is frequently used to access isotopically labeled compounds with broad utility in many research areas, such as drug development, mechanistic studies, and NMR analyses. Nevertheless, the deuteration of a stereocenter in an enantios...

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Publicado en:iScience
Autores principales: Shao, Tianju, Li, Yajuan, Ma, Nana, Li, Chunyang, Chai, Guobi, Zhao, Xiaowei, Qiao, Baokun, Jiang, Zhiyong
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593145/
https://ncbi.nlm.nih.gov/pubmed/31229890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.007
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