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Formal enantioconvergent substitution of alkyl halides via catalytic asymmetric photoredox radical coupling

Classic nucleophilic substitution reactions (S(N)1 and S(N)2) are not generally amenable to the enantioselective variants that use simple and racemic alkyl halide electrophiles. The merging of transition metal catalysis and radical chemistry with organometallic nucleophiles is a versatile method for...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Jiangtao, Kong, Manman, Qiao, Baokun, Lee, Richmond, Zhao, Xiaowei, Jiang, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015005/
https://ncbi.nlm.nih.gov/pubmed/29934495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04885-3
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