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Design, synthesis and evaluation of [(111)In]-labeled, DOTA-conjugated tetrapeptides having high affinity and selectivity for mu opioid receptors
INTRODUCTION: Peripheral mu (μ) opioid receptors are implicated in pain, bowel dysfunction and the progression of certain cancers. In an effort to identify radioligands well suited for imaging these peripheral sites, we have prepared and evaluated four hydrophilic [(111)In]-labeled, DOTA (1,4,7,10-t...
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| Publicado en: | Nucl Med Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591026/ https://ncbi.nlm.nih.gov/pubmed/30933866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2019.02.001 |
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