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Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with (111)In in HEPES and MES buffer

BACKGROUND: In single photon emission computed tomography [SPECT], high specific activity of (111)In-labelled tracers will allow administration of low amounts of tracer to prevent receptor saturation and/or side effects. To increase the specific activity, we studied the effect of the buffer used dur...

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Detalhes bibliográficos
Main Authors: Brom, Maarten, Joosten, Lieke, Oyen, Wim JG, Gotthardt, Martin, Boerman, Otto C
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292493/
https://ncbi.nlm.nih.gov/pubmed/22284727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-4
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