(68)Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET

PURPOSE: Insulinomas are neuroendocrine tumours derived from pancreatic β-cells. The glucagon-like peptide 1 receptor (GLP-1R) is expressed with a high incidence (>90%) and high density in insulinomas. Glucagon-like peptide 1 (GLP-1), the natural ligand of GLP-1R, is rapidly degraded in vivo. A m...

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Détails bibliographiques
Auteurs principaux: Brom, Maarten, Oyen, Wim J. G., Joosten, Lieke, Gotthardt, Martin, Boerman, Otto C.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2010
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886138/
https://ncbi.nlm.nih.gov/pubmed/20111963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1363-y
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