mTORC1 promotes metabolic reprogramming by suppression of GSK3-dependent Foxk1 phosphorylation

The mammalian Target Of Rapamycin Complex 1 (mTORC1) signaling system plays a critical role in maintenance of cellular homeostasis by sensing and integrating multiple extracellular and intracellular cues. Therefore, uncovering the effectors of mTORC1 signaling is pivotal to understanding its pathoph...

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Publicado en:Mol Cell
Autores principales: He, Long, Gomes, Ana P., Wang, Xin, Yoon, Sang Oh, Lee, Gina, Nagiec, Michal, Cho, Sungyun, Chavez, Andre, Islam, Tasnia, Yu, Yonghao, Asara, John M., Kim, Bo Yeon, Blenis, John
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591025/
https://ncbi.nlm.nih.gov/pubmed/29861159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.024
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