Loading...

Reactive cysteine residues in the oxidative dimerization and Cu(2+) induced aggregation of human γD-crystallin: Implications for age-related cataract

Cysteine (Cys) residues are major causes of crystallin disulfide formation and aggregation in aging and cataractous human lenses. We recently found that disulfide linkages are highly and partly conserved in β-and γ-crystallins, respectively, in human age-related nuclear cataract and glutathione depl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta Mol Basis Dis
Main Authors: Ramkumar, Srinivasagan, Fan, Xingjun, Wang, Benlian, Yang, Sichun, Monnier, Vincent M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590075/
https://ncbi.nlm.nih.gov/pubmed/30251679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.08.021
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!