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Altered aggregation properties of mutant γ-crystallins cause inherited cataract

Protein inclusions are associated with a diverse group of human diseases ranging from localized neurological disorders through to systemic non-neuropathic diseases. Here, we present evidence that the formation of intranuclear inclusions is a key event in cataract formation involving altered γ-crysta...

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Detaylı Bibliyografya
Asıl Yazarlar: Sandilands, Aileen, Hutcheson, Aileen M., Long, Heather A., Prescott, Alan R., Vrensen, Gijs, Löster, Jana, Klopp, Norman, Lutz, Raimund B., Graw, Jochen, Masaki, Shigeo, Dobson, Christopher M., MacPhee, Cait E., Quinlan, Roy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC137201/
https://ncbi.nlm.nih.gov/pubmed/12426373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf609
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