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Precision Control of CRISPR-Cas9 Using Small Molecules and Light

The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is an adaptive immune system of bacteria that has furnished several RNA-guided DNA endonucleases (e.g., Cas9) that are revolutionizing the field of genome engineering. Cas9 is being used to effect genomic alterations as...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Gangopadhyay, Soumyashree A., Cox, Kurt J., Manna, Debasish, Lim, Donghyun, Maji, Basudeb, Zhou, Qingxuan, Choudhary, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586488/
https://ncbi.nlm.nih.gov/pubmed/30640437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01202
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