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Multidimensional chemical control of CRISPR–Cas9

Cas9-based technologies have transformed genome engineering and the interrogation of genomic functions, but methods to control such technologies across numerous dimensions—including dose, time, specificity, and mutually exclusive modulation of multiple genes—are still lacking. We conferred such mult...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Maji, Basudeb, Moore, Christopher L, Zetsche, Bernd, Volz, Sara E, Zhang, Feng, Shoulders, Matthew D, Choudhary, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531067/
https://ncbi.nlm.nih.gov/pubmed/27820801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2224
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