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A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9
Several genome engineering applications of CRISPR-Cas9, an RNA-guided DNA endonuclease, require precision control of Cas9 activity over dosage, timing, and targeted site in an organism. While some control of Cas9 activity over dose and time have been achieved using small molecules, and spatial contr...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7067309/ https://ncbi.nlm.nih.gov/pubmed/30834641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201900788 |
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