L-Selectin Enhanced T Cells Improve the Efficacy of Cancer Immunotherapy

The homing molecule, L-selectin (CD62L), is commonly used as a T cell activation marker, since expression is downregulated following engagement of the T cell receptor. Studies in mice have shown that CD62L(+) central memory T cells are better at controlling tumor growth than CD62L(−) effector memory...

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Udgivet i:Front Immunol
Main Authors: Watson, H. Angharad, Durairaj, Ruban R. P., Ohme, Julia, Alatsatianos, Markella, Almutairi, Hanan, Mohammed, Rebar N., Vigar, Miriam, Reed, Sophie G., Paisey, Stephen J., Marshall, Christopher, Gallimore, Awen, Ager, Ann
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582763/
https://ncbi.nlm.nih.gov/pubmed/31249570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01321
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