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L-selectin Is Essential for Delivery of Activated CD8(+) T Cells to Virus-Infected Organs for Protective Immunity

Cytotoxic CD8(+) T lymphocytes play a critical role in the host response to infection by viruses. The ability to secrete cytotoxic chemicals and cytokines is considered pivotal for eliminating virus. Of equal importance is how effector CD8(+) T cells home to virus-infected tissues. L-selectin has no...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mohammed, Rebar N., Watson, H. Angharad, Vigar, Miriam, Ohme, Julia, Thomson, Amanda, Humphreys, Ian R., Ager, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742564/
https://ncbi.nlm.nih.gov/pubmed/26804910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.090
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