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Development of a Carbon-11 PET Radiotracer for Imaging TRPC5 in the Brain

The transient receptor potential channels subfamily member 5 (TRPC5) is a calcium permeable cation channel widely expressed in the brain. Accumulating evidence indicates that it plays a crucial role in psychiatric disorders including depression and anxiety. Positron emission tomography (PET) combini...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Org Biomol Chem
Hauptverfasser: Yu, Yanbo, Liang, Qianwa, Liu, Hui, Luo, Zonghua, Hu, Hongzheng, Perlmutter, Joel S., Tu, Zhude
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582641/
https://ncbi.nlm.nih.gov/pubmed/31115430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00893d
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