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Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate
The radiosyntheses and in vivo evaluation of four carbon-11 labeled quinoline group-containing radioligands are reported here. Radiolabeling of [(11)C]1–4 was achieved by alkylation of their corrsponding desmethyl precursors with [(11)C]CH(3)I. Preliminary biodistribution evaluation in Sprague–Dawle...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054929/ https://ncbi.nlm.nih.gov/pubmed/24721831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.03.028 |
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