Kinetics Modeling and Occupancy Studies of a Novel C-11 PET Tracer for VAChT in Nonhuman Primates

INTRODUCTION: Deficits in cholinergic function have been found in the aged brain and in neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The vesicular acetylcholine transporter (VAChT) is a reliable biomarker for the cholinergic system. We previously report...

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Publicat a:Nucl Med Biol
Autors principals: Jin, Hongjun, Zhang, Xiang, Yue, Xuyi, Liu, Hui, Li, Junfeng, Yang, Hao, Flores, Hubert, Su, Yi, Parsons, Stanley M., Perlmutter, Joel S., Tu, Zhude
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753027/
https://ncbi.nlm.nih.gov/pubmed/26872437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2015.11.003
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