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Kinetic modeling of [(18)F]VAT, a novel radioligand for PET imaging vesicular acetylcholine transporter (VAChT) in nonhuman primate brain

Molecular imaging of vesicular acetylcholine transporter (VAChT) in the brain provides an important cholinergic biomarker for the pathophysiology and treatment of dementias including Alzheimer’s disease (AD). In this study, kinetics modeling methods were applied and compared for quantifying regional...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Jin, Hongjun, Yue, Xuyi, Liu, Hui, Han, Junbin, Flores, Hubert, Su, Yi, Parsons, Stanley M., Perlmutter, Joel S., Tu, Zhude
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897141/
https://ncbi.nlm.nih.gov/pubmed/29315563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14291
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