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The impact of dopamine D(2)-like agonist/antagonist on [(18)F]VAT PET measurement of VAChT in the brain of nonhuman primates

Vesicular acetylcholine transporter (VAChT) is a promising target for a PET measure of cholinergic deficits which contribute to cognitive impairments. Dopamine D(2)-like agonists and antagonists are frequently used in the elderly and could alter cholinergic function and VAChT level. Therefore, pretr...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Liu, Hui, Luo, Zonghua, Gu, Jiwei, Su, Yi, Flores, Hubert, Parsons, Stanley M., Zhou, Yun, Perlmutter, Joel S., Tu, Zhude
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980745/
https://ncbi.nlm.nih.gov/pubmed/31740395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2019.105152
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