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Development of a Carbon-11 PET Radiotracer for Imaging TRPC5 in the Brain

The transient receptor potential channels subfamily member 5 (TRPC5) is a calcium permeable cation channel widely expressed in the brain. Accumulating evidence indicates that it plays a crucial role in psychiatric disorders including depression and anxiety. Positron emission tomography (PET) combini...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Yu, Yanbo, Liang, Qianwa, Liu, Hui, Luo, Zonghua, Hu, Hongzheng, Perlmutter, Joel S., Tu, Zhude
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582641/
https://ncbi.nlm.nih.gov/pubmed/31115430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00893d
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