Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T cells and Tregs

CD4 T cells play a critical role in promoting the development of autoimmunity in Type 1 Diabetes (T1D). The diabetogenic CD4 T cell clone BDC-2.5, originally isolated from a non-obese diabetic (NOD) mouse, has been widely used to study the contribution of autoreactive CD4 T cells and relevant antige...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Jamison, Braxton L., Neef, Tobias, Goodspeed, Andrew, Bradley, Brenda, Baker, Rocky L., Miller, Stephen D., Haskins, Kathryn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581587/
https://ncbi.nlm.nih.gov/pubmed/31109955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900127
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