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Hybrid insulin peptides are neo-epitopes for CD4 T cells in autoimmune diabetes

PURPOSE OF REVIEW: The current review covers recent advances in our knowledge of the newest autoantigen neo-epitopes in type 1 diabetes (T1D): hybrid insulin peptides or HIPs. These ligands for autoreactive T cells are formed by peptide fusion, a novel posttranslational modification process that we...

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Publicado en:Curr Opin Endocrinol Diabetes Obes
Autores principales: Baker, Rocky L., Jamison, Braxton L., Haskins, Kathryn
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830731/
https://ncbi.nlm.nih.gov/pubmed/31166225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0000000000000490
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