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Tregs epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity
Reprogramming autoreactive CD4+ effector T (Teff) cells into immunosuppressive Tregs represents a promising strategy for treating established autoimmune diseases. However, the stability and function of such reprogrammed Tregs under inflammatory conditions remain unclear. Here, we show that demethyla...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical investigation
2025-09-01
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| Σειρά: | JCI Insight |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1172/jci.insight.185581 |
| Ετικέτες: |
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