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Azacitidine mitigates GvHD via differential effects on the proliferation of T effectors and nTregs in vivo

Azacitidine (AzaC) mitigates Graft vs. Host Disease (GvHD) in both murine preclinical transplant models and in human clinical trials while maintaining a robust Graft vs. Leukemia (GvL) effect. Previous studies have failed to investigate the role of natural Tregs on the mitigation of GvHD by AzaC; in...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Cooper, Matthew L., Choi, Jaebok, Karpova, Darja, Vij, Kiran, Ritchey, Julie, Schroeder, Mark A., DiPersio, John F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541679/
https://ncbi.nlm.nih.gov/pubmed/28330901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502399
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