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The breadth of HIV-1 neutralizing antibodies depends on the conservation of key sites in their epitopes

Developing HIV-1 vaccines that trigger broadly neutralizing antibodies (bnAbs) is a priority as bnAbs are considered key to elicitation of a protective immune response. To investigate whether the breadth of a neutralizing antibody (nAb) depended on the conservation of its epitope among circulating v...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Bai, Hongjun, Li, Yifan, Michael, Nelson L., Robb, Merlin L., Rolland, Morgane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581281/
https://ncbi.nlm.nih.gov/pubmed/31170145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007056
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