Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

Major advances in donor identification, antigen probe design, and experimental methods to clone pathogen-specific antibodies have led to an exponential growth in the number of newly characterized broadly neutralizing antibodies (bnAbs) that recognize the HIV-1 envelope glycoprotein. Characterization...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Cheng, Hao D., Grimm, Sebastian K., Gilman, Morgan S.A., Gwom, Luc Christian, Sok, Devin, Sundling, Christopher, Donofrio, Gina, Hedestam, Gunilla B. Karlsson, Bonsignori, Mattia, Haynes, Barton F., Lahey, Timothy P., Maro, Isaac, von Reyn, C. Fordham, Gorny, Miroslaw K., Zolla-Pazner, Susan, Walker, Bruce D., Alter, Galit, Burton, Dennis R., Robb, Merlin L., Krebs, Shelly J., Seaman, Michael S., Bailey-Kellogg, Chris, Ackerman, Margaret E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922287/
https://ncbi.nlm.nih.gov/pubmed/29515029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97018
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