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Dynamic changes in histone deacetylases following kidney ischemia-reperfusion injury are critical for promoting proximal tubule proliferation

Deranged histone deacetylase (HDAC) activity causes uncontrolled proliferation, inflammation, fibrosis, and organ damage. It is unclear whether deranged HDAC activity results in acute kidney injury in the renal hypoperfusion model of bilateral ischemia-reperfusion injury (IRI) and whether in vivo in...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Main Authors: Hyndman, Kelly A., Kasztan, Malgorzata, Mendoza, Luciano D., Monteiro-Pai, Sureena
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580243/
https://ncbi.nlm.nih.gov/pubmed/30810062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00499.2018
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